沈育芳 | Yu-Fang Shen
Status Full Time Faculty
Name 沈育芳 | Yu-Fang Shen
Email cherryuf@gmail.com
Job title Assistant Professor
Education PhD in Chemistry, National Chung Hsing University, Taiwan
Expertise Chemistry
Research Areas Cell and molecular biology,  medical engineering,  biomedical imaging, 3D printing
Office HB50
Phone +886-423323456 ext.20050
Websites Office HourWebpageTeacher Eportfolio
Year Paper Title
2022 Pei-Chun Wu、Lun-Zhang Guo、Shan Yu、Ning Zeng、Yu-Cheng Liu、Jia Yu、Zhiming Zhang、Ke Lu、Liangyu Sun、Chunfei Wang、沈育芳(Yu-Fang Shen), Noninvasive Assessment of Liver Function Reserve with Fluorescent Dosimetry of Indocyanine Green, Biomedical Optics Express, vol.13 no.4 pp.1995-2005
2021 陳怡文(Yi-Wen Chen)、 Ming-You Shie、Wen-Ching Chang、沈育芳(Yu-Fang Shen)*, Approximate Optimization Study of Light Curing Waterborne Polyurethane Materials for the Construction of 3D Printed Cytocompatible Cartilage Scaffolds, Materials, vol.14 no.22 pp.6804-
2021 Cheng-Ham Wu、Kristina S. Kisel、Muthu Kumar Thangavel、Yi-Ting Chen、Kai-Hsin Chang、Ming-Rung Tsai、Chia-Yu Chu、沈育芳(Yu-Fang Shen)、Pei-Chun Wu、Zhiming Zhang、Tzu-Ming Liu(Tzu-Ming Liu)*, Functionalizing collagen with vessel-penetrating two-photon phosphorescence probes: A new in vivo strategy to map oxygen concentration in tumor microenvironment and tissue ischemia, Advanced Science, vol.8 no.20 pp.e2102788-
2019 Wei Long Ng、Jia Min Lee、Miaomiao Zhou、Yi-Wen Chen、Kai-Xing Alvin Lee、Waiyee Yeong、沈育芳(Yu-Fang Shen)*, Vat polymerization-based bioprinting – process, materials, applications and regulatory challenges, Biofabrication
2019 謝明佑(Ming-You Shie)、沈育芳(Yu-Fang Shen)、Suryani Dyah Astuti、Alvin Kai-Xing Lee、Shu-Hsien Lin、Ni Luh Bella Dwijaksara、陳怡文(Yi-Wen Chen)*, Review of Polymeric Materials in 4D Printing Biomedical Applications, Polymers, vol.11 pp.1864-
2019 Wei Long Ng、Chee Kai Chua、沈育芳(Yu-Fang Shen)*, Print Me An Organ! Why Are We Not There Yet, PROGRESS IN POLYMER SCIENCE, vol.97 pp.101145-
2019 Yung-Cheng Chiu、沈育芳(Yu-Fang Shen)、Alvin Kai-Xing Lee、Shu-Hsien Lin、Yu-Chen Wu、Yi-Wen Chen(Yi-Wen Chen)*, 3D Printing of Amino Resin-based Photosensitive Materials on Multi-parameter Optimization Design for Vascular Engineering Applications, Polymers, vol.11 pp.1394-
2019 陳怡文(Yi-Wen Chen)、Hsin-Yuan Fang、謝明佑(Ming-You Shie)、沈育芳(Yu-Fang Shen)*, The Mussel-Inspired Assisted Apatite Mineralized on Polyjet Material for Artificial Bone Scaffold, International Journal of Bioprinting, vol.5 no.2 pp.197-
2019 沈育芳(Yu-Fang Shen)、謝明佑(Ming-You Shie)、陳怡文(Yi-Wen Chen)*, 3D 成型技術之介紹與應用, 科儀新知, vol.219 pp.90-98
2019 Tsui-Hsien Huang、Chia-Tze Kao、沈育芳(Yu-Fang Shen)、Yi-Ting Lin、Yen-Ting Liu、Ssu-Yin Yen、Chia-Che Ho(Chia-Che Ho)*, Substitutions of strontium in bioactive calcium silicate bone cements stimulate osteogenic differentiation in human mesenchymal stem cells, Journal of Materials Science: Materials in Medicine, vol.30 pp.68-
2019 Zhong Xun Khoo、Jia An、Chee Kai Chua、沈育芳(Yu-Fang Shen)、郭哲男(Che-Nan Kuo)*、 Yong Liu, Effect of Heat Treatment on Repetitively Scanned SLM NiTi Shape Memory Alloy, Materials, vol.12 no.1 pp.77-
2018 陳怡文(Yi-Wen Chen)、沈育芳(Yu-Fang Shen)、Chia-Che Ho、Joyce Yu、Yuan-Haw Andrew Wu、Kan Wang、Cheng-Ting Shih、謝明佑(Ming-You Shie)*, Osteogenic and angiogenic potentials of the cell-laden hydrogel/mussel-inspired calcium silicate complex hierarchical porous scaffold fabricated by 3D bioprinting, Materials Science and Engineering C, vol.91 pp.679-687
2018 沈育芳(Yu-Fang Shen)、Tsui-Hsien Huang、Hooi-Yee Ng、Hsin-Yuan Fang、Tuan-Ti Hsu(Tuan-Ti Hsu)*, Mineral Trioxide Aggregate Mixed with 5-Aminolevulinic Acid for the Photodynamic Antimicrobial Strategy in Hard Tissue Regeneration, Materials, vol.11 pp.1734-
2018 Hooi Yee Ng、Kai-Xing Alvin Lee、郭哲男(Che-Nan Kuo)、沈育芳(Yu-Fang Shen)*, Bioprinting of artificial blood vessels, International Journal of Bioprinting, vol.4 no.2 pp.140-
2018 Zhong Xun Khoo、Yong Liu、Jia An、Chee Kai Chua、沈育芳(Yu-Fang Shen)、郭哲男(Che-Nan Kuo)*, A Review of Selective Laser Melted NiTi Shape Memory Alloy, Materials, vol.11 no.4 pp.519-
2018 Pei-Chun Wu、沈育芳(Yu-Fang Shen)、Chi-Kuang Sun、Charles P. Lin、Tzu-Ming Liu(Tzu-Ming Liu)*, Harmonic generation microscopy of bone microenvironment in vivo, OPTICS COMMUNICATIONS, vol.422 pp.52-55
2017 Yen-Hong Lin、Yung-Cheng Chiu、沈育芳(Yu-Fang Shen)、Yuan-Haw Andrew Wu、謝明佑(Ming-You Shie)*, Bioactive calcium silicate/poly-ε-caprolactone composite scaffolds 3D printed under mild conditions for bone tissue engineering, Journal of Materials Science: Materials in Medicine, vol.29 pp.11-
2017 M. Shie、沈育芳(Yu-Fang Shen)、C. Chen、Y. Chen(Y. Chen)*, A 3D-printed Multi-channel Conduit for Peripheral Nerve Repair, Tissue Engineering Part A, vol.23 pp.S45-
2017 S. Yen、M. Shie、沈育芳(Yu-Fang Shen)、Y. Chen(Y. Chen)*, Evaluation of Bilayer 3D Printed Scaffold in Osteochondral Regeneration, Tissue Engineering Part A, vol.23 pp.S45-
2017 沈育芳(Yu-Fang Shen)、Yu-Chen Wu、謝明佑(Ming-You Shie)、陳怡文(Yi-Wen Chen)*, 3D Printed Biphasic Elastomeric Scaffolds with Cell-Laden Hydrogels for Blood Vessel Tissue Engineering, Tissue Engineering Part A, vol.23 pp.S-46-S-47
2017 Kai-Xing Alvin Lee、Hooi Yee Ng、沈育芳(Yu-Fang Shen)*, Tissue Engineered Cartilage Constructs for Cartilage Regeneration, JSM Bone and Joint Diseases, vol.1 pp.1009-
2017 Hooi Yee Ng、Kai-Xing Alvin Lee、沈育芳(Yu-Fang Shen)*, Articular Cartilage: Structure, Composition, Injuries and Repair, JSM Bone and Joint Diseases, vol.1 pp.1010-
2017 Yuan-Chien Chen、謝明佑(Ming-You Shie)、Yuan-Haw Andrew Wu c、Kai-Xing Alvin Lee、Li-Ju Wei c、沈育芳(Yu-Fang Shen)*, Anti-inflammation performance of curcumin-loaded mesoporous calcium silicate cement, JOURNAL OF THE FORMOSAN MEDICAL ASSOCIATION, vol.116 pp.679-688
2017 謝明佑(Shie, M.-Y.)、Chang, W.-C.、Wei, L.-J.、Huang, Y.-H.、Chen, C.-H.、Shih, C.-T.、Chen, Y.-E.、沈育芳(Yu-Fang Shen)*, 3D printing of cytocompatible water-based light-cured polyurethane with hyaluronic acid for cartilage tissue engineering applications, Materials, vol.10 no.2 pp.136-
2016 Ming-Hsien Huang、沈育芳(Yu-Fang Shen)、Tuan-Ti Hsu、Tsui-Hsien Huang(Tsui-Hsien Huang)*, Physical characteristics, antimicrobial and odontogenesis potentials of calcium silicate cement containing hinokitiol, Materials Science & Engineering C-Materials for Biological Applications, vol.65 pp.1-8
2016 沈育芳(Yu-Fang Shen)、Gan-Hong Chen、Shu-Hsien Lin、Gialih Lin(Gialih Lin)*, S-endo-2-Norbornyl-N-n-butylcarbamate as a Potential Pseudomonas Lipase Inhibitor to Probe the Enantioselectivity of the Enzyme by Kinetic and Molecular Docking Evaluation, JOURNAL OF THE CHINESE CHEMICAL SOCIETY, vol.63 pp.709-715
2016 沈育芳(Yu-Fang Shen)、Chia-Che Ho、Ming-You Shie、Kan Wang、Hsin-Yuan Fang(Hsin-Yuan Fang)*, Hinokitiol-loaded mesoporous calcium silicate nanoparticle induce apoptotic cell death through regulation of the function of MDR1 in lung adenocarcinoma cells, Materials, vol.9 pp.306-
2016 Shang-Wei Chou、Chien-Liang Liu、Tzu-Ming Liu、沈育芳(Yu-Fang Shen)、Kuo, Lun-Chang、Cheng-Ham Wu、Tsung-Yuan Hsieh、Pei-Chun Wu、Ming-Rung Tsai ,、Kai-Yao Chang、Meng-Hau Lu、Pai-Chi Li、Shi-Ping Chen, Infrared-Active Quadruple Contrast FePt Nanoparticles for Multiple Scale Molecular Imaging, BIOMATERIALS, vol.85 pp.54-64
2016 沈育芳(Yu-Fang Shen)、Gan-Hong Chen、Shu-Hsien Lin、Gialih Lin(Gialih Lin)*, Molecular modeling and docking calculations of 4-acyloxy-biphenyl-4′-N-butylcarbamates as potential inhibitors into human butyrylcholinesterase, CANADIAN JOURNAL OF CHEMISTRY, vol.94 no.1 pp.72-77
2015 沈育芳(Yu-Fang Shen)、Ming-Rung Tsai、Shao-Chieh Chen、Yun-Shiuan Leung、Chien-Tai Hsieh、Yu-Shing Chen、Fu-Lien Huang、Rofeamor P. Obena、Medel Manuel L. Zulueta,、Wen-Jeng Lee、Kuo-Chun Tang、Chun-Ta Kung、Min-Huey Chen, Imaging Endogenous Bilirubins with Two-Photon Fluorescence of Bilirubin Dimers, ANALYTICAL CHEMISTRY, vol.87 pp.7575-7582
2012 Lin, M.-C.、Lin, G.-Z.、Hwang, C.-I.、Jian, S.-Y.、Lin, J.、沈育芳(Yu-Fang Shen)、Lin, G.(Lin, G.)*, Synthesis and Evaluation of a New Series of tri-, di-, and mono-N-alkylcarbamylphloroglucinols as Conformationally Constrained Inhibitors, PROTEIN SCIENCE, vol.21 pp.1344-1357
2012 Lin, M.-C.、Lin, G.-Z.、沈育芳(Yu-Fang Shen)、Jian, S.-Y.、Hsieh, D.-K.、Lin, J.、Lin, G.(Lin, G.)*, Synthesis and Evaluation of a New Series of tri-, di-, and mono-N-alkylcarbamylphloroglucinols as Bulky Inhibitors of Acetylcholinesterase, CHEMICAL RESEARCH IN TOXICOLOGY, vol.25 pp.1462-1471
2011 Lin, M.-C.、沈育芳(Yu-Fang Shen)、Lin, G.(Lin, G.)*, Synthesis and Pseudomonas Lipase Inhibition Study of Stereoisomers of decahydro-2-naphthyl-N-n-butylcarbamate, PROTEIN AND PEPTIDE LETTERS, vol.18 pp.1168-1176
2011 沈育芳(Yu-Fang Shen)、Chen, Y.-H.、Chu, S.-Y.、Lin, M.-I.、Hsu, H.-T.、Wu, P.-Y.、Wu, C.-J.、Liu, H.-W.、Hsu, P.-H.、Yang, A.-S.、Cheng, Y.-S. E.、Wu, Y.-T., E339...R416 Salt Bridge of Nucleoprotein as a Feasible Target for Influenza Virus Inhibitors, PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, vol.108 pp.16515-16520
2011 沈育芳(Yu-Fang Shen)、Lin, G.(Lin, G.)*, Kinetics and Protein-Inhibitor Docking Studies of Enantiomers of exo-2-Norbornyl-N-n-butylcarbamates as Pseudomonas Lipase Inhibitors to Probe the Enantioselectivity of the Enzyme, JOURNAL OF THE CHINESE CHEMICAL SOCIETY, vol.59 pp.60-65
Year Book Title
2017 沈育芳(Yu-Fang Shen), Functional 3D Tissue Engineering Scaffolds, 3D functional scaffolds for cartilage tissue engineering, Elsevier, 2017/01
Date of Publication Paper Title
2021.11 Wan Ni Huang、Yi Wen Chen、Ming You Shie、沈育芳(Yu-Fang Shen), 3D Cell Building Blocks in Cancer Drug Evaluation Applications , Annual Meeting of Taiwanese Society of Biomedical Engineering and The 3rd International Symposium on Engineering and Technology, Taiwan/National Chung Hsing University
2021.11 Yu-Hsiang Liao、Ming-You Shie、Yi-Wen Chen、沈育芳(Yu-Fang Shen), 3D Cell Building Blocks in the Application of Artificial Dermis , Annual Meeting of Taiwanese Society of Biomedical Engineering and The 3rd International Symposium on Engineering and Technology, Taiwan/National Chung Hsing University
2019.05 陳怡文(Yi-Wen Chen)、謝明佑(Ming-You Shie)、洪偉哲、沈育芳(Yu-Fang Shen), 3D Printed Hybrid Multilayer Scaffolds with Cell, encapsulating Hydrogels for Cartilage Tissue Engineering - 183RD International Academy of Science, Technology, Engineering and Management (IASTEM) International Conference on Chemical and Biochemical Engineering, Las Vegas, USA
2018.11 Hong, W.-C.、Wang, W.-H.、謝明佑(Ming-You Shie)、陳怡文(Yi-Wen Chen)、沈育芳(Yu-Fang Shen), 3D, printed Hyaluronic Acid / Waterborne Polyurethane Light Cured Hybrid Scaffolds for Cartilage Tissue Engineering - Global Conference on Biomedical Engineering, Chung Yuan Christian University, Taiwan
2018.11 Hong, W.-C.、Wang, W.-H.、謝明佑(Ming-You Shie)、陳怡文(Yi-Wen Chen)、沈育芳(Yu-Fang Shen), 3D, printed Light-Cured Waterborne Polyurethane/ Hydrogel Hybrid Scaffolds for Cartilage Tissue Engineering - Global Conference on Biomedical Engineering, Chung Yuan Christian University, Taiwan
2018.11 Huang, X.-T.、Lee, K.-X. A.、Chang, P.、Lin, G.、沈育芳(Yu-Fang Shen), 3D Quantitative Structure, activity Relationship Studies and Molecular Docking Evaluation of Carbamates as Inhibitors of Acetylcholinesterase - Global Conference on Biomedical Engineering, Chung Yuan Christian University, Taiwan
2018.09 沈育芳(Yu-Fang Shen)、Wang, W.-H.、Hong, W.-C.、Lin, M.-Y.、Hong, W.-C.、Lai, Y.-H.、 Liu, C.-W.、謝明佑(Ming-You Shie)、陳怡文(Yi-Wen Chen), 3D Hybrid Multilayer Scaffolds for Cartilage , 5th TERMIS - World Congress-2018, Kyoto, Japan
2017.11 洪偉哲、王偉皇、林明毅、洪菀婧、劉鈞維、賴友和、謝明佑(Ming-You Shie)、陳怡文(Yi-Wen Chen)、沈育芳(Yu-Fang Shen), 具有封裝細胞的水凝膠之混合式支架在軟骨組織工程的應用 , 2017生物醫學工程科技研討會, 台灣/桃園/中央大學
2017.10 WH Wang、MY Shie、YW Chen, 3D Printed Porous Hybrid Scaffolds by Stereolithographic Fabrication for Cartilage Tissue Engineering , 2017 International Conference on Biofabrication, China/Beijing
2017.09 Wei-Huang Wang、Ming-You Shie、Yi-Wen Chen, 3D Printed Scaffolds for Cartilage Tissue Engineering , 2017 International Conference of Developmental Biology, Stem Cells and Regenerative Medicine - from Basic Research to Applications, Academia Sinica, Taipei. Taiwan
2017.08 沈育芳(Yu-Fang Shen)、Wei-Huang Wang、Yi-Wen Chen、Ming-You Shie, 3D Printed Scaffolds for Cartilage Tissue Engineering , 2017 International Symposium of Materials on Regenerative Medicine, 台灣/桃園/渴望會館
2017.08 Kai-Xing Alvin Lee、Yu-Chen Wu、Wei-Huang Wang、Yi-Wen Chen、沈育芳(Yu-Fang Shen), 3D Printed Biphasic Elastomeric Scaffolds for Blood Vessel Tissue Engineering , 2017 International Symposium of Materials on Regenerative Medicine, 台灣/桃園/渴望會館
Project Title Participator Period
開發含有自銅藻萃取之褐藻醣膠之膠原蛋白/硫酸軟骨素/幾丁聚醣之三維海綿敷料於全皮膚損傷修復之應用 (OAC-111-001) 沈育芳(Yu-Fang Shen) 2022.05 ~ 2022.11
乳癌晶片精準醫療用於患者臨床藥物確效試驗評估 (CMU-AIC-V1.1) 沈育芳(Yu-Fang Shen) 2021.12 ~ 2022.11
以細胞積木開發3D皮膚組織藥妝檢測平台 (ASIA-110-CMUH-06) 沈育芳(Yu-Fang Shen)、李建智 2021.11 ~ 2022.10
以細胞積木開發具膚色的三維人工皮膚於大面積損傷之應用 (110-2221-E-468 -003 -) 沈育芳(Yu-Fang Shen) 2021.08 ~ 2022.07
發展三維細胞積木於癌症藥物篩選及組織再生之應用 (108-2221-E-468-016-MY2) 沈育芳(Yu-Fang Shen) 2020.08 ~ 2021.07
積層製造結合精準醫療於癌症藥物篩檢平台之應用(3/3) (108-2218-E-039-001) 陳怡文(Yi-Wen Chen)、王潔、 鄭逸琳、沈育芳(Yu-Fang Shen)、 張穎宜 2019.08 ~ 2020.07
發展三維細胞積木於癌症藥物篩選及組織再生之應用 (108-2221-E-468-016-MY2) 沈育芳(Yu-Fang Shen) 2019.08 ~ 2020.07
玻尿酸/水性聚氨酯光固化軟骨複合支架開發(2/2) (108-2622-E-468-001-CC2) 沈育芳(Yu-Fang Shen) 2019.06 ~ 2020.05
以光固化型水性聚氨酯和具有封裝細胞的水凝膠發展混合式多層支架在軟骨組織再生的應用 (107-2218-E-468 -005 - ) 沈育芳(Yu-Fang Shen) 2018.08 ~ 2019.07
玻尿酸/水性聚氨酯光固化軟骨複合支架開發(1/2) (MOST 107-2622-E-468-002 -CC2│) 沈育芳(Yu-Fang Shen) 2018.06 ~ 2019.05
三維建模及設計軟體開發應用於臨床精準醫療應用(3/3) (MOST 106 - 2218 - E - 468 - 001 -) 黃仲陵(Chung-Lin Huang)、林維暘、陳玉菁(YU-CHING CHEN)、沈育芳(Yu-Fang Shen)、郭哲男(Che-Nan Kuo)、莊政宏(Cheng-Hung Chuang)、謝長倭(Chang-Wei Hsieh)、蔡淵裕(Yuan-Yu Tsai)、龍希文、林智揚(CHIH-YANG LIN)、陳怡文(Yi-Wen Chen) 2017.11 ~ 2018.10
積層製造結合精準醫療於癌症藥物篩檢平台之應用(1/3) (106-3114-E-039 -001 -) 陳怡文(Yi-Wen Chen)、王潔、鄭逸琳、沈育芳(Yu-Fang Shen)、謝明佑(Ming-You Shie)、張穎宜 2017.09 ~ 2018.07
自動化三維脊椎模型優化與建置 (ASIA-105-CMUH-05) 沈育芳(Yu-Fang Shen)、陳賢德 2016.10 ~ 2017.09
Award Name Awarding Unit
第十八屆國家新創獎-新創精進獎 財團法人生技醫療科技政策研究中心
2021未來科技獎 請選擇
第十七屆國家新創獎-新創精進獎 財團法人生技醫療科技政策研究中心
第十七屆國家新創獎 財團法人生技醫療科技政策研究中心
第十六屆國家新創獎 財團法人生技醫療科技政策研究中心
第十五屆國家新創獎 財團法人生技醫療科政策研究中心
喬福材料 3D列印創作競賽 喬福集團
Category Course Code Course Title Year
Bachelor's programs XDU00232A 積層製造概論 111
Bachelor's programs GRG00093T 資訊與科技 111
Bachelor's programs EB301050A 組織工程(IISMA計畫) 111
Bachelor's programs EB301048A 數位3D建模實作(就業) 111
Bachelor's programs EB301039A 醫學工程實驗 111
Bachelor's programs EB301027A 3D列印市場原理及產品開發(就業) 111
Bachelor's programs EB301002A 高分子材料學 111
Bachelor's programs EB300963A 學輔時間(二) 111
Bachelor's programs EB300769A 基礎生物化學 111
Doctoral Program EB100967A 生醫材料概論 111
Year Project name Advising professor Department Student name
110 口畫家水彩筆咬筆輔具開發
108 臂神經叢損傷患者手部輔具開發 沈育芳 生醫系 李尚庭
107 客製化踝足裝具之設計與開發 沈育芳 生物資訊與醫學工程學系 賴友和
Publish Date Patent Title Patent Number
2019/08/11 含細胞之三維體的製造方法及其堆疊方法 中華民國發明專利:I668002
2018/08/01 握筆輔具 中華民國新型專利:M564529